UCSF Helen Diller Family Comprehensive Cancer Center

Photo of Wallace Marshall, PhD  Wallace Marshall, PhD

Associate Professor, Department of Biochemistry and Biophysics, UCSF

Contact

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(415) 514-4304
(415) 502-4315 (fax) (fax)

Box 2200, San Francisco, CA 94143-2200

Additional websites:
    Marshall Lab

Education

State University of New York at Stony Brook, BE, 1991, Electrical Engineering
State University of New York at Stony Brook, BS, 1991, Biochemistry
University of California, San Francisco, PhD, 1997, Biochemistry
Yale University, New Haven CT, Postdoc, 1997-2003, Cell Biology

Professional Experience

  • 2003-2009
    Assistant Professor of Biochemistry & Biophysics, UCSF
  • 2009-present
    Associate Professor of Biochemistry & Biophysics, UCSF

Honors & Awards

  • Eta Kappa Nu Electrical Engineering Honor Society, 1990
  • Howard Hughes Medical Institute Predoctoral Fellowship, 1991 - 1996
  • Helen Hay Whitney Foundation Fellowship, 1997 - 2000
  • Leukemia & Lymphoma Society Special Fellowship, 2000-2003
  • Searle Scholar Award, 2005-2008
  • Dean's Recognition for Excellence in Teaching, School of Pharmacy, 2007, 2008
  • W.M Keck Foundation Distinguished Young Scholar in Medical Research, 2007
  • Herbert Boyer Junior Faculty Endowed Chair, 2009

Selected Publications

  • Marshall, W.F. and Rosenbaum, J.L. 2001. Intraflagellar transport balances continuous turnover of outer doublet microtubules: implications for flagellar length control. J. Cell Biol. 155,405-414.
  • Zamora, I., Feldman, J.L, and Marshall, W.F. 2004. PCR-based assay for mating type and diploidy in Chlamydomonas. Biotechniques 37, 534-6.
  • Stolc, V., Samanta, M.P., Tongprasit, W., and Marshall, W.F. 2005. Genome-wide transcriptional analysis of flagellar regeneration in Chlamydomonas reinhardtii identifies orthologs of ciliary disease genes. Proc. Natl. Acad. Sci. U.S.A. 102,3703-3707.
  • Keller, L.C., Romijn, E.P., Zamora, I., Yates, J.R. 3rd., and Marshall, W.F. 2005. Proteomic analysis of isolated Chlamydomonas centrioles reveals orthologs of ciliary disease genes. Curr. Biol. 15,1090-8.
  • Zamora, I., and Marshall, W.F. 2005. A mutation in the centriole-associated protein centrin causes genomic instability via increased chromosome loss. BMC Biology. 3,15.
  • Marshall, W.F., Qin, H., Rodrigo Brenni, M., and Rosenbaum, J.L. 2005. Flagellar length control system: testing a simple model based on intraflagellar transport and turnover. Mol. Biol. Cell 16, 270-8.
  • Feldman, J.L, Geimer, S., and Marshall, W.F. 2007. The mother centriole plays an instructive role in defining cell geometry. PLoS Biology. 5,e149.
  • Marshall, W.F. 2007. Stability and robustness of an organelle number control system: modeling and measuring homeostatic regulation of centriole abundance. Biophys. J. 93,1818-33.
  • Merchant, S., Prochnik, S., Vallon, O., Harris, E.H., Karpowicz, S.J., Witman, G.B., Terry, A., Salamov, A., Fritz-Laylin, L.K., Marechal-Drouard, L., Marshall, W.F., et al., 2007. The Chlamydomonas genome reveals evolutionary insights into key animal and plant functions. Science. 318, 245-50.
  • Marshall, W.F. 2008. Modeling recursive RNA interference. PLoS Computational Biol. 4, e1000183.
  • Keller, L.C., Geimer, S., Romijn, E., Yates, J., Zamora, I., and Marshall, W.F. 2009. Molecular architecture of the centriole proteome: The conserved WD40 domain protein POC1 is required for centriole duplication and length control. Mol. Biol. Cell 20, 1150-66.
  • Feldman, J.L., and Marshall, W.F. 2009. ASQ2 encodes a TBCC-like protein required for mother-daughter centriole linkages and mitotic spindle orientation. Curr. Biol. 19, 1238-43.
  • Marshall, W.F. 2009. Quantitative high-throughput assays for flagella-based motility in Chlamydomonas using plate-well image analysis and transmission correlation spectroscopy. J. Biomol. Screening 14, 133-41.
  • Engel, B.D., Ludington, W., and Marshall, W.F. 2009. Intraflagellar transport particle size scales inversely with flagellar length: revisiting the balance-point length control model. J. Cell Biol. 187, 81-9.
  • Keller, L.C., Wemmer, K.A., and Marshall, W.F. 2010. Influence of centriole number on mitotic spindle length and symmetry. Cytoskeleton. 67, 504-18.

Updated: December 20, 2011