Tarik Tihan, MD, PhD

University of Istanbul, School of Medicine, MD, 1979-85, Medicine
University of Istanbul/Univ. Of Vienna, PhD, 1986-89, Biochemistry

• 1985-1986
  Kahramanmaras State Hospital, Department of Critical Care, Turkey. House Officer.
• 1986-1989
  University of Istanbul, Istanbul Medical School, Department of Clinical Biochemistry. Clinical Instructor and Research Assistant.
• 1988-1989
  University of Vienna, Department of Medical Chemistry, Austria. Research Assistant. Research Grant from the Austrian government, Ministry of Education, (Bundesministerium fuer Auswaertige Angelegenheiten).
• 1989
  Doctorate, University of Istanbul, Department of Clinical Biochemistry. Diplomate of the Ministry of Health and Social Aid for the medical doctorate in Clinical Biochemistry.
• 1989-1990
  University of South Florida, Department of Internal Medicine & H. Lee Moffitt Cancer Center. Research Associate.
• 1991-1992
  Beth Israel Medical Center, Department of Neurosurgery. Manager of the Recanati Research Laboratory.
• 1992-1994
  Beth Israel Medical Center, Department of Pathology, Resident
• 1994-1995
  Memorial Sloan-Kettering Cancer Center, Department of Pathology. Fellow in Oncologic Pathology.
• 1996
  American Board of Pathology Certificate of Anatomic Pathology.
• 1995-1997
  State University of New York at Stony Brook, Department of Pathology. Fellow in Neuropathology.
• 1997-2000
  Johns Hopkins Medical Institutions, Department of Pathology, Clinical Instructor. Johns Hopkins Bayview Medical Center, Department of Pathology. Attending Pathologist in Anatomic Pathology and Cytopathology.
• 2000-2002
  Johns Hopkins Medical Institutions, Department of Pathology, Assistant Professor
• 2002-present
  UCSF School of Medicine, Department of Pathology, Neuropathology Unit, Associate Professor
• 2002-present
  Principal Investigator, Brain Tumor Research Center, Department of Neurological Surgery

• 2001-2003
  John Hopkins W. Barry Wood Jr, Award in excellence in teaching
• 2003
  USCF Department of Pathology Teaching Excellence Award
• 2003, 2005
  UCSF Department of Neurological Surgery Teaching Excellence in Basic Science Award

• Blouw B, Song H, Tihan T et al. The hypoxic response of tumors is dependent on their microenvironment. Cancer Cell. 2003;4:133-46. Byrne NP, Parney IF, Chang SM, Tihan T. Spinal cord ependymomas: The UCSF experience (Abstract). J Neuropathol Exp Neurol. 2003;62:571.
• Byrnes CK, Bahadursingh A, Akhter N et al. Duodenal reflux produces hyperproliferative epithelial esophagitis--a possible precursor to esophageal adenocarcinoma in the rat. J Gastrointest Surg. 2003;7:172-80.
• Eberhart CG, Cohen KJ, Tihan T, Goldthwaite PT, Burger PC. Medulloblastomas with systemic metastases: evaluation of tumor histopathology and clinical behavior in 23 patients. J Pediatr Hematol Oncol. 2003;25:198-203.
• Kaiser A, Spence RJ, Parwani A, Tihan T, Barrett TL. Basaloid follicular hamartoma with trichoblastomatous proliferations. J Cutan Med Surg. 2003;7:395-8.
• Li KW, Dang W, Tyler BM et al. Polilactofate microspheres for Paclitaxel delivery to central nervous system malignancies. Clin Cancer Res. 2003;9:3441-7.
• Lucey BP, Tihan T, Pomper MG, Olivi A, Laterra J. Spinal meningioma causing diffuse leptomeningeal enhancement. Neurology. 2003;60:350-1.
• McDonald WM, Nigro JM, Lin D et al. Glial neoplasms resembling oligodendroglioma in children:Does pediatric oligodendroglioma exist? (Abstract). J Neuropathol Exp Neurol. 2003;62:571.
• Tihan T, Viglione M, Rosenblum MK, Olivi A, Burger PC. Solitary fibrous tumors in the central nervous system. A clinicopathologic review of 18 cases and comparison to meningeal hemangiopericytomas. Arch Pathol Lab Med. 2003;127:432-9.
• Waldron JS, Tihan T. Pathology and Epidemiology of Intraventricular Tumors. Neurosurg Clin N Am. 2003;14:469-482.
• Frazier J, Garonzik I, Tihan T, Olivi A. Recurrent glioependymal cyst of the posterior fossa: an unusual entity containing mixed glial elements. Case report. J Neurooncol. 2004;68:13-7.
• Horvath Z, Hochtl T, Bauer W et al. Synergistic cytotoxicity of the ribonucleotide reductase inhibitor didox (3,4-dihydroxy-benzohydroxamic acid) and the alkylating agent carmustine (BCNU) in 9L rat gliosarcoma cells and DAOY human medulloblastoma cells. Cancer Chemother Pharmacol. 2004;54:139-45.
• Horvath Z, Bauer W, Hoechtl T et al. Combination chemotherapy of BCNU and Didox acts synergystically in 9L glioma cells. Nucleosides Nucleotides Nucleic Acids. 2004;23:1531-5.
• Komotar RJ, Burger PC, Carson BS et al. Pilocytic and pilomyxoid hypothalamic/chiasmatic astrocytomas. Neurosurgery. 2004;54:72-9; discussion 79-80.
• Komotar RJ, Mocco J, Carson BS et al. Pilomyxoid astrocytoma: a review. MedGenMed. 2004;6:42.
• Watson MA, Perry A, Tihan T et al. Gene expression profiling reveals unique molecular subtypes of NF Type I-associated and sporadic malignant peripheral nerve sheath tumors. Brain Pathol. 2004;14:297-303.
• Abel TW, Baker SJ, Fraser MM et al. Lhermitte-Duclos disease: a report of 31 cases with immunohistochemical analysis of the PTEN/AKT/mTOR pathway. J Neuropathol Exp Neurol. 2005;64:341-9.
• Calcagnotto ME, Paredes MF, Tihan T, Barbaro NM, Baraban SC. Dysfunction of synaptic inhibition in epilepsy associated with focal cortical dysplasia. J Neurosci. 2005;25:9649-57.
• Cha S, Tihan T, Crawford F et al. Differentiation of low-grade oligodendrogliomas from low-grade astrocytomas by using quantitative blood-volume measurements derived from dynamic susceptibility contrast-enhanced MR imaging. AJNR Am J Neuroradiol. 2005;26:266-73.
• Crain BJ, Alston SR, Bruch LA et al. Accreditation council for graduate medical education (ACGME) competencies in neuropathology training. J Neuropathol Exp Neurol. 2005;64:273-9.
• Haas-Kogan DA, Prados MD, Tihan T et al. Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib. J Natl Cancer Inst. 2005;97:880-7.
• Haas-Kogan DA, Prados MD, Lamborn KR, Tihan T, Berger MS, Stokoe D. Biomarkers to Predict Response to Epidermal Growth Factor Receptor Inhibitors. Cell Cycle. 2005;4.
• Komotar RJ, Carson BS, Rao C, Chaffee S, Goldthwaite PT, Tihan T. Pilomyxoid astrocytoma of the spinal cord: report of three cases. Neurosurgery. 2005;56:191.
• Komotar RJ, Mocco J, Jones JE et al. Pilomyxoid astrocytoma: diagnosis, prognosis, and management. Neurosurg Focus. 2005;18:E7.
• Sanchez-Mejia RO, Pham DN, Prados M et al. Management of a Sporadic Malignant Subfrontal Peripheral Nerve Sheath Tumor. J Neurooncol. 2005.
• Tihan T, Vohra P, Berger MS, Keles GE. Definition and Diagnostic Implications of Gemistocytic Astrocytomas: a Pathological Perspective. J Neurooncol. 2005.
• Wang M, Tihan T, Rojiani AM et al. Monomorphous angiocentric glioma: a distinctive epileptogenic neoplasm with features of infiltrating astrocytoma and ependymoma. J Neuropathol Exp Neurol. 2005;64:875-81.